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Stride Health Group
Stride Health Group Ltd
Company No 05158025
Lamas Road
Badersfield
Norwich
England
NR10 5FB
UK
Biomarkers A–Z
Browse our biomarker library from A to Z. Learn what each biomarker measures, why it matters, and which Stride tests include it.
A
The ACE gene test analyses DNA for the common insertion/deletion (I/D) polymorphism (rs4646994 or rs4340) that affects how your body produces…
Active B12 is a functional B12 marker that measures the fraction of vitamin B12 that is bound to transcobalamin and available for your cells to use. Because it…
The ACTN3 gene test analyses DNA for variants in the ACTN3 gene that determine whether you produce alpha-actinin-3 in fast-twitch muscle fibres. Knowing your…
The ADA gene test analyses DNA for variants in adenosine deaminase, a key enzyme in purine metabolism that controls adenosine and deoxyadenosine levels and…
The ADH1C gene test analyses DNA for common variants in the alcohol dehydrogenase 1C gene that influence how efficiently you convert ethanol into acetaldehyde…
The ADORA2 gene test analyses DNA for variants in the adenosine A2A receptor gene that influence how your brain and body respond to adenosine and to caffeine,…
The ADRB2 gene test analyses DNA for common variants in the beta-2 adrenergic receptor gene that influence how your body responds to adrenaline and similar…
The AGT gene test analyses DNA for variants in the angiotensinogen gene that influence how your body regulates blood pressure, fluid balance, and the…
Alanine transferase ALT, also called alanine aminotransferase, is an enzyme found mainly in your liver cells. An ALT blood test is one of the core liver health…
An albumin blood test measures the level of albumin, the main protein in your blood plasma, made by your liver. Albumin helps keep fluid inside your blood…
The ALDOB gene test analyses DNA for variants in the aldolase B gene that control how your liver, kidney, and small intestine break down dietary fructose.…
Alkaline phosphatase ALP is an enzyme found mainly in your liver and bones, with smaller amounts in your intestines, kidneys, and placenta. An ALP blood test…
Anti-TG (thyroglobulin antibodies) is a thyroid autoimmunity marker that detects antibodies directed against thyroglobulin, the protein your thyroid uses to…
The APOA2 gene test analyses DNA for variants in the apolipoprotein A2 gene that influence HDL composition, lipid metabolism, and how your body responds to…
The APOA5 gene test analyses DNA for variants in the apolipoprotein A5 gene that strongly influence fasting and post-meal triglyceride levels and the behaviour…
ApoB is a heart health blood marker that measures the number of atherogenic ("artery-entering") cholesterol particles circulating in your bloodstream. Because…
The APOC3 gene test analyses DNA for variants in the apolipoprotein C3 gene that influence how your body handles triglyceride-rich lipoproteins and remnant…
The APOE gene test analyses DNA for the e2, e3, and e4 variants of apolipoprotein E, a key lipid transport protein that also shapes brain ageing and dementia…
Apolipoprotein A1 ApoA1 is a heart health blood marker that reflects the amount of protective HDL cholesterol particles helping to remove cholesterol from your…
The Apolipoprotein B/A1 Ratio ApoB/A1 is a heart health blood marker that compares the amount of plaque driving cholesterol particles ApoB to the amount of…
Aspartate transferase AST, also called aspartate aminotransferase, is an enzyme found in your liver, heart, and muscles. An AST blood test is a core part of…
B
A basophils blood test measures how many basophils you have in your blood, reported as both a percentage of white blood cells and an absolute count. Basophils…
The BCMO1 gene test analyses DNA for variants in beta-carotene monooxygenase 1, the key enzyme that converts plant provitamin A carotenoids such as beta…
The BCO1 gene test analyses DNA for variants in the beta-carotene oxygenase 1 gene that influence how efficiently you convert plant carotenoids, such as…
The BDKRB2 gene test analyses DNA for variants in the bradykinin receptor B2 gene that influence how strongly your blood vessels dilate, how efficiently…
The BDNF gene test analyses DNA for variants in brain-derived neurotrophic factor, a key growth factor that supports neuron survival, synaptic plasticity, and…
The BHMT gene test analyses DNA for variants in betaine--homocysteine methyltransferase that can alter how efficiently you remethylate homocysteine to…
A bilirubin blood test measures the level of bilirubin, a yellow pigment produced when your body breaks down old red blood cells. Bilirubin is processed by the…
C
A calcium blood test measures how much calcium is circulating in your bloodstream, not stored in your bones. It is a key marker for bone health, parathyroid…
The CAT gene test analyses DNA for common genetic variants in the catalase gene that can influence how efficiently your cells break down hydrogen peroxide, a…
The CBS gene test analyses DNA for variants in cystathionine beta synthase that can alter how efficiently you convert homocysteine into cystathionine in the…
The CETP gene test analyses DNA for variants in cholesteryl ester transfer protein, a key lipid transfer protein that moves cholesteryl esters and…
A chloride blood test measures the level of chloride, a key electrolyte, circulating in your bloodstream. Chloride works alongside sodium, potassium, and…
The CLOCK gene test analyses DNA for variants in the circadian clock gene that regulates your 24-hour biological rhythm and controls the timing of sleep,…
The COL1A1 gene test analyses DNA for variants in the collagen type I alpha 1 gene that influence the quantity and quality of type I collagen in bone and…
The COL5A1 gene test analyses DNA for variants in the collagen type V alpha 1 gene that influence the structure and organisation of collagen fibrils in…
COMT (catechol O methyltransferase) is a gene that helps your body break down key neurotransmitters and stress hormones such as dopamine, norepinephrine, and…
Cortisol is a stress and adrenal health hormone that helps regulate your energy, blood pressure, immune response, and metabolism throughout the day. A cortisol…
A creatinine blood test measures the level of creatinine, a waste product from normal muscle activity, in your bloodstream. Because healthy kidneys filter…
The CRP gene test analyses DNA for variants in the C-reactive protein gene that influence how much CRP your liver produces in response to inflammatory signals.…
The CYP1A2 gene test analyses DNA for common genetic variants that influence how actively your liver enzyme CYP1A2 metabolises caffeine, many prescribed…
The CYP4F2 gene test analyses DNA for variants in the cytochrome P450 4F2 gene that influence vitamin K metabolism, blood pressure regulation, and dose…
D
The DCAF5 gene test analyses DNA for variants in DDB1 and CUL4 associated factor 5, a substrate receptor within the CUL4--DDB1 (CRL4) E3 ubiquitin ligase…
D.H.E.A. sulphate, usually written as DHEAS, is an adrenal androgen that your body uses as a building block to make other sex hormones, including testosterone…
The DHFR gene test analyses DNA for variants in dihydrofolate reductase that can alter how efficiently you recycle folate into its active forms to support DNA…
E
Estimated glomerular filtration rate eGFR is a calculation that uses your creatinine blood test, age, sex, and body size to estimate how well your kidneys…
The ELN gene test analyses DNA for variants in elastin, the core protein that gives large arteries, lungs, and skin their elastic recoil. Understanding your…
An eosinophils blood test measures how many eosinophils you have in your blood, reported as both a percentage of white blood cells and as an absolute count.…
The EPHX1 gene test analyses DNA for variants in the microsomal epoxide hydrolase 1 gene that influence how effectively your body converts reactive epoxides…
F
The FABP2 gene test analyses DNA for variants in the intestinal fatty acid binding protein 2 gene that influence how your gut absorbs and traffics dietary long…
The FBXL3 gene test analyses DNA for variants in an F-box and leucine rich repeat protein that helps control the stability of core clock proteins such as…
Ferritin is a protein that safely stores iron inside your cells and releases it when needed. A ferritin blood test gives a window into your iron stores,…
The FKBP5 gene test analyses DNA for variants in FK506 binding protein 5 (FKBP51), a co chaperone that helps regulate glucocorticoid receptor sensitivity and…
Folate, also known as vitamin B9, is a B vitamin that supports red blood cell production, DNA and RNA synthesis, and healthy development of the nervous system.…
The Free Androgen Index (FAI) is a hormone marker that estimates how much free, biologically active testosterone is available in your bloodstream. It helps…
FT3 (Free Triiodothyronine) is a thyroid hormone marker that measures the unbound, biologically active form of T3 circulating in your blood. It provides a…
FT4 (Free Thyroxine) is a thyroid hormone marker that measures the unbound, biologically active form of thyroxine circulating in your blood. It is one of the…
The FTO gene test analyses DNA for common variants in the fat mass and obesity associated gene that influence appetite regulation, energy balance, and how…
The FUT2 gene test analyses DNA for variants in fucosyltransferase 2 that determine your secretor status, meaning whether you express ABO blood group antigens…
G
Gamma GT GGT, also called gamma glutamyl transferase, is an enzyme found mainly in your liver and bile ducts and in smaller amounts in your kidneys, pancreas,…
The GDF5 gene test analyses DNA for variants in the growth differentiation factor 5 gene that influence how your joints, cartilage, tendons, and ligaments…
A globulin blood test measures a group of proteins in your blood that includes antibodies, transport proteins, and inflammatory proteins. Globulins sit…
A random glucose test measures the amount of glucose circulating in your blood at any point in the day, regardless of when you last ate. It gives a quick…
The GLUT2 gene test analyses DNA for variants in SLC2A2, which encodes glucose transporter 2, a low affinity, high capacity transporter that sits at the…
The GPX1 gene test analyses DNA for common genetic variants in the glutathione peroxidase 1 gene that can influence how efficiently your cells use glutathione…
The GSS gene test analyses DNA for variants in glutathione synthetase, the enzyme that catalyses the final step in glutathione synthesis and helps maintain…
The GSTM1 gene test analyses DNA for a common insertion/deletion variant that determines whether you produce functional glutathione S-transferase Mu 1 enzyme…
The GSTT1 gene test analyses DNA for a common insertion/deletion variant that determines whether you produce functional glutathione S-transferase Theta 1…
H
A haematocrit blood test HCT measures what percentage of your blood is made up of red blood cells. Because red blood cells carry oxygen, your haematocrit…
A haemoglobin blood test measures the amount of haemoglobin, the iron containing protein in red blood cells that carries oxygen from your lungs to the rest of…
HbA1c, also called glycated haemoglobin or haemoglobin A1c, is a blood marker that reflects your average blood sugar levels over the past 2 to 3 months. It is…
The HCRTR2 gene test analyses DNA for variants in the hypocretin (orexin) receptor 2, a brain receptor that helps control wakefulness, sleep stability,…
HDL percentage of total cholesterol HDL % of Total Cholesterol is a calculated heart health marker that shows how much of your total cholesterol is made up of…
HDL cholesterol, often called the "good" cholesterol, is a blood lipid marker that reflects the amount of protective high density lipoprotein particles in your…
The HFE gene test analyses DNA for variants in the homeostatic iron regulator gene that influence how your body senses iron and controls absorption from the…
The HLA DQ2/DQ8 gene test analyses DNA for specific HLA class II haplotypes that are strongly associated with coeliac disease and related gluten driven…
High sensitivity C reactive protein hsCRP is a blood marker of low grade inflammation that can help refine cardiovascular risk and give insight into how your…
The HTR2A gene test analyses DNA for variants in the serotonin 2A receptor, a major excitatory serotonin receptor that shapes mood, sleep, cognition, and how…
I
The IL6 gene test analyses DNA for variants in the interleukin 6 gene that influence how strongly you generate IL-6, a key cytokine that drives inflammation,…
The IL6R gene test analyses DNA for variants in the interleukin 6 receptor gene that shape how IL-6 signals in your body through classic and trans-signalling…
The INSIG gene test analyses DNA for variants in the insulin induced genes INSIG1 and INSIG2 that influence how tightly your cells control cholesterol and…
An iron blood test looks at how much iron is circulating in your blood and how your body is transporting and using it. On its own it offers a snapshot of…
L
The LCT/MCM6 gene test analyses DNA for variants in the lactase (LCT) gene and its regulatory regions in the MCM6 gene that determine whether you maintain…
LDL cholesterol, often called the "bad" cholesterol, is a blood lipid marker that reflects the amount of cholesterol carried by low density lipoprotein…
The LEPR gene test analyses DNA for variants in the leptin receptor, a key signalling hub for body weight regulation, appetite, energy expenditure, and…
The LINC00461 gene test analyses DNA for variants near LINC00461, a brain enriched long non coding RNA that helps regulate neurodevelopment, hippocampal…
The LIPC gene test analyses DNA for variants in hepatic lipase, a key enzyme that remodels HDL and intermediate-density lipoproteins and helps regulate…
Lipoprotein (a), often written as Lp(a), is a genetically driven cholesterol particle that can significantly increase cardiovascular risk even when standard…
The LPL gene test analyses DNA for variants in lipoprotein lipase, the key enzyme that clears triglycerides from the bloodstream and helps shape HDL, LDL, and…
Luteinising Hormone (LH) is a key reproductive hormone produced by the pituitary gland that helps regulate ovulation in women and testosterone production in…
M
Magnesium is a mineral and electrolyte that plays a central role in energy production, muscle and nerve function, heart rhythm and bone health. A magnesium…
The MAOA gene test analyses DNA for variants in monoamine oxidase A that can change how efficiently you break down key neurotransmitters such as serotonin,…
The MAOB gene test analyses DNA for variants in monoamine oxidase B that can alter how efficiently you break down dopamine and other monoamine and trace…
The MC1R gene test analyses DNA for variants in the melanocortin 1 receptor, a key regulator of skin and hair pigmentation and ultraviolet light response.…
The MC4R gene test analyses DNA for variants in the melanocortin 4 receptor, a central regulator of appetite, satiety, and energy expenditure in the brain.…
Mean corpuscular haemoglobin MCH is the average amount of haemoglobin in each red blood cell. Because haemoglobin carries oxygen, your MCH result helps show…
Mean corpuscular haemoglobin concentration MCHC is the average concentration of haemoglobin inside your red blood cells. Because haemoglobin carries oxygen,…
Mean corpuscular volume MCV is the average size of your red blood cells. Because red blood cell size changes in different types of anaemia and nutrient…
Mean platelet volume MPV is the average size of your platelets, the blood cells that help your blood clot and repair vessel damage. MPV adds nuance to a…
The MEIS1 gene test analyses DNA for variants in a developmental transcription factor that strongly influence risk for restless legs syndrome, periodic limb…
The MIR2113 gene test analyses DNA for variants near microRNA 2113, a brain expressed microRNA locus that has been associated with general cognitive function,…
The MMP1 gene test analyses DNA for variants in matrix metalloproteinase 1, a key collagenase that breaks down interstitial collagens and shapes how tissues…
The MMP3 gene test analyses DNA for variants in matrix metalloproteinase 3, a stromal enzyme that degrades many extracellular matrix proteins and activates…
A monocytes blood test measures how many monocytes you have in your blood, reported as both a percentage of white blood cells and an absolute count. Monocytes…
The MTHFD1 gene test analyses DNA for variants in methylenetetrahydrofolate dehydrogenase 1 that can alter how efficiently your cells process one carbon units…
The MTHFR gene test analyses DNA for common genetic variants (C677T and A1298C) that can reduce enzyme activity and influence how your body processes folate,…
MTR (methionine synthase) is a gene that provides the instructions for an enzyme that converts homocysteine back into methionine, sitting at the heart of…
N
The NBPF3 gene test analyses DNA for variants in the neuroblastoma breakpoint family member 3 gene that are associated with vitamin B6 metabolism and…
A neutrophils blood test measures how many neutrophils you have in your blood, reported as both a percentage of white blood cells and an absolute count.…
The NOS1 gene test analyses DNA for variants in neuronal nitric oxide synthase 1, the main source of nitric oxide in the brain and a key regulator of vascular…
The NOS3 gene test analyses DNA for variants in endothelial nitric oxide synthase that can alter how efficiently your blood vessels produce nitric oxide from L…
The NRF gene test (often referred to as Nrf2 or NFE2L2) analyses DNA for variants in the NRF2 transcription factor that influence how effectively your cells…
O
Oestradiol is the most active form of oestrogen in the body and a core hormone for menstrual cycles, fertility, bone density, brain health and long term…
The OXTR gene test analyses DNA for variants in the oxytocin receptor, a key regulator of social bonding, stress buffering, empathy, and emotional regulation.…
P
The PEMT gene test analyses DNA for variants in phosphatidylethanolamine N methyltransferase that can change how efficiently your liver converts…
The PER2 gene test analyses DNA for variants in the period 2 clock gene that can influence intrinsic circadian period, chronotype, and susceptibility to sleep…
The PER3 gene test analyses DNA for common variants in the period 3 clock gene that can influence sleep architecture, chronotype (morningness or eveningness),…
A platelet blood test measures how many platelets you have in your bloodstream. Platelets are tiny cell fragments that help your blood clot and your blood…
The PLCL1 gene test analyses DNA for variants in phospholipase C like protein 1, an intracellular signalling protein that binds inositol phosphates and helps…
The PLIN gene test analyses DNA for common variants in the perilipin 1 gene that influence how your fat cells store and release triglycerides on the surface of…
The PPARA gene test analyses DNA for variants in the peroxisome proliferator-activated receptor alpha (PPAR-alpha) gene that influence how efficiently your…
The PPARG gene test analyses DNA for common and rare variants in the peroxisome proliferator-activated receptor gamma gene that can influence how your body…
The PPARGC1A gene test analyses DNA for variants in the peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1a) gene that shape how…
Progesterone is a key reproductive hormone that prepares the body for pregnancy, stabilises the uterine lining and supports early gestation. A progesterone…
Prolactin is a hormone made by the pituitary gland that is best known for its role in breast development and milk production, but it also affects fertility,…
R
The RASD1 gene test analyses DNA for variants in a dexamethasone induced small G protein that sits at the intersection of stress signalling, nitric oxide…
Red blood cell count is a core blood health marker that measures the total number of red blood cells circulating in a given volume of your blood. These cells…
Red cell distribution width RDW describes how much your red blood cells vary in size. When RDW is combined with haemoglobin, MCV, and other red cell indices,…
The RGS16 gene test analyses DNA for variants in regulator of G protein signaling 16, a protein that switches off specific G protein coupled receptor signals…
The RNASEL gene test analyses DNA for variants in the ribonuclease L pathway that can alter how your cells respond to viral infections and regulate cellular…
S
Sex Hormone Binding Globulin (SHBG) is a protein made by the liver that tightly binds sex hormones like testosterone and oestradiol in the bloodstream. By…
The SLC23A1 gene test analyses DNA for variants in the sodium-dependent vitamin C transporter 1 (SVCT1) gene that influence how effectively you absorb and…
The SOD2 gene test analyses DNA for variants in superoxide dismutase 2, the mitochondrial enzyme that converts superoxide radicals from energy production into…
A sodium blood test measures the amount of sodium dissolved in your blood. Sodium is the main salt in the bloodstream and is crucial for fluid balance, blood…
T
T4 (thyroxine) is the main hormone produced by your thyroid gland and a central driver of metabolism, energy use and temperature regulation. A T4 blood test…
The TAS2R38 gene test analyses DNA for common genetic variants in the bitter taste receptor 38 gene that influence how strongly you perceive specific bitter…
The TCF7L2 gene test analyses DNA for common variants in the transcription factor 7-like 2 gene that can markedly influence your lifetime risk of type 2…
The TCN2 gene test analyses DNA for variants in transcobalamin 2, the main transport protein that carries vitamin B12 from the gut and bloodstream into cells…
Testosterone is a key sex and anabolic hormone that shapes energy, libido, muscle mass, mood, red blood cell production and body composition in both men and…
The TF gene test analyses DNA for variants in the transferrin gene that influence how your body transports iron in the bloodstream and delivers it to tissues.…
The TFR2 gene test analyses DNA for variants in the transferrin receptor 2 gene that influence how your liver senses circulating iron and regulates hepcidin.…
The TMPRSS6 gene test analyses DNA for variants in the matriptase-2 gene that influence how your body regulates hepcidin and absorbs iron from the gut.…
The TNF gene test analyses DNA for variants in the tumor necrosis factor gene that influence how strongly you produce TNF alpha, a central cytokine that drives…
Total cholesterol is a blood marker that reflects the overall amount of cholesterol carried in your bloodstream across all lipoproteins. It is one of the…
Total iron binding capacity TIBC is an iron study that estimates how much iron your blood could carry if all iron transport proteins were fully loaded. Because…
A total protein blood test measures the combined amount of the two main protein groups in your blood, albumin and globulins. These proteins help maintain fluid…
Thyroid peroxidase TPO antibodies are immune proteins directed against the thyroid peroxidase enzyme inside the thyroid gland. When raised, they strongly…
Transferrin saturation is an iron study that shows what percentage of your main iron transport protein, transferrin, is filled with iron. It helps clarify…
The TRHR gene test analyses DNA for variants in the thyrotropin-releasing hormone receptor gene that influence how sensitively your pituitary responds to TRH…
Triglycerides are a type of blood fat that store excess energy from your diet and circulate in your bloodstream inside lipoprotein particles. When triglyceride…
TSH, or thyroid stimulating hormone, is a pituitary hormone that tells your thyroid gland how hard to work. A TSH blood test is the front door into thyroid…
U
Unsaturated iron binding capacity UIBC shows how much spare capacity your main iron transport protein, transferrin, still has to bind iron. Together with serum…
A urea blood test sometimes reported as blood urea or BUN measures how much urea a waste product from protein breakdown is circulating in your blood. Because…
V
The VDR gene test analyses DNA for variants in the vitamin D receptor that can influence how effectively your cells respond to vitamin D, shaping calcium…
The VEGF gene test analyses DNA for variants in the vascular endothelial growth factor gene that influence how readily your body grows, remodels, and maintains…
The VIP gene test analyses DNA for variants in the vasoactive intestinal peptide pathway that can shape how your brain and body regulate circadian rhythm,…
A vitamin D blood test measures the level of 25 hydroxyvitamin D 25 OH D in your blood, which is the best indicator of your overall vitamin D status. Vitamin D…
W
White blood cell count is a core immune health marker that measures the total number of white blood cells circulating in your blood. These immune cells help…
X
The XKR6 gene test analyses DNA for variants in XK related protein 6, a predicted membrane protein involved in exposing phosphatidylserine on the surface of…
Z
The ZPR1 gene test analyses DNA for variants in the ZPR1 zinc finger gene that influence how effectively cells respond to growth signals and support survival…
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Methylation & Cellular Health
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