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DNA & Methylation Test Let's see what you're made of.

Your methylation, decoded. See how efficiently your body uses folate and other B vitamins, with insight into genes like MTHFR, MTR, MAOA and COMT.

A bottle of MS-01 daily methylation support stack

Free gift

Free MS-01 with every test order

A 4-week supply, added to your order automatically — nothing to add, nothing to pay.

From £109.85 1:1 expert consultation included · Results in 10 working days

MS-01 gift with health tests and bundles, excluding Optimal DNA Link (23andMe).

One gene never tells the whole story.

MTHFR, COMT, MTR and up to 107 more genes, read together and turned into one plan.

We read up to 110 genes side by side. Then a practitioner turns them into a short, simple plan.

What is methylation?

Methylation is a natural process that helps your body decide what to do, when to do it, and how well to do it. It works like a set of switches inside your cells, turning key processes up or down as needed, including energy production, detoxification, repair, and recovery.

  1. Small switches, big jobs

    Small markers (called methyl groups) are added to parts of your DNA and other molecules. They don’t change who you are. They simply help your body prioritise what needs attention.

  2. Why it matters

    When methylation is working well, your body is better at producing energy, clearing toxins, repairing cells, and staying resilient as you age.

  3. Where your genes come in

    Your genes shape how efficiently your methylation cycles are likely to run, starting with how you convert folate (vitamin B9) into its usable form. Nutrition, lifestyle and stress all play a role too, so there’s plenty you can do with what you learn.

Choose your level.

Every level reads your core methylation pathways and includes a 1:1 expert consultation. Higher levels add more of your genetic picture.

  • 19 genes

    Core

    A clear starting point, focused on methylation

    • All five methylation cycles
    • Not included: Nutrition & metabolism insights
    • Not included: Fitness, sleep & stress insights
    • 1:1 expert consultation
    • Free MS-01 4-week supply

    £169£109.85

  • 59 genes

    Advanced

    Methylation plus deeper nutrition insight

    • All five methylation cycles
    • Nutrition & metabolism insights
    • Not included: Fitness, sleep & stress insights
    • 1:1 expert consultation
    • Free MS-01 4-week supply

    £269£174.85

  • Most popular

    110 genes

    Optimal

    The complete picture across your biology

    • All five methylation cycles
    • Nutrition & metabolism insights
    • Fitness, sleep & stress insights
    • 1:1 expert consultation
    • Free MS-01 4-week supply

    £319£207.35

Compare all three levels

As featured in

Financial Times Forbes The Telegraph Fitt Insider Sheerluxe The Standard Red Country & Town House Luxurious Magazine InTouch Rugby

How it works.

Four simple steps, with a practitioner waiting at the end.

  1. Step 1

    Order your kit

    Delivered to your door in 1–2 days.

  2. Step 2

    Swab at home

    A simple cheek swab, then send it back to us.

  3. Step 3

    Accredited specialist lab

    Analysed privately and securely, with results in 10 working days.

  4. Step 4

    Your results and plan

    Your reports land in MyStride, then a 1:1 consultation turns them into a plan.

What you get.

A practitioner in your corner.

Every level includes a 1:1 video consultation with a Stride expert, so your results become a short, practical plan.

A Stride health expert on a video consultation, with action items from the call

Results in 10 working days.

We'll let you know the moment your reports are ready.

A hiker on a summit, with a notification that StrideDNA test results are ready

Reports you can actually read.

Up to 45 reports across methylation, nutrition, fitness, sleep and stress, all in MyStride.

The Folate Cycle report open in MyStride on a tablet

Supplements, matched to your results.

Methylated, high-absorption formulas, so acting on your plan is simple.

Stride SD-01, MS-01 and GS-01 supplements

Join our community of biotrackers taking control of their health

Real reviews from Stride users.

Ambassadors

Trusted by the leading minds in health and performance

From clinical pioneers to Olympic champions, Stride is the preventative health system backed by those who know best.

Dr William Li

“What excites me about Stride is how we can show people what’s happening inside their bodies and then use diet and lifestyle change to transform their future towards optimal health. It’s a platform that turns science into daily practice.”

Dr William Li

Physician, Scientist & BESTSELLING AUTHOR

Dr Rupy Aujla

“Stride is the service that finally connects the dots between testing, lifestyle and real-world behaviour change. Most services give you data; Stride gives you direction. This is the kind of preventative, personalised approach we need more of.”

Dr Rupy Aujla

NHS GP & Founder of The Doctor’s Kitchen

Greg Rutherford

“As Olympic champion, I learned that the smallest details can be the difference between good and great. Now that I’m at a different stage of my life, what I love about Stride is that it brings that same performance mindset to everyday health.”

Greg Rutherford, MBE

Olympic Gold Medallist & Broadcaster

The StrideOne box beside the Stride DNA and Stride Biome test kits

Want the whole picture?

StrideOne is one membership: a 360° picture of your biology, a practitioner in your corner, and supplements made to match. Retested over time, so you can see what’s working.

From £549 every 6 months

Discover StrideOne

Or start somewhere else.

Test your gut or your blood, or pair DNA with gut in one kit.

  • Optimal Biome

    In-depth microbiome testing

    From £399 £279.30

    + Free MS-01 4-week supply

  • Optimal Bloods

    70+ blood biomarker testing

    From £399 £279.30

    + Free MS-01 4-week supply

  • Optimal Duo

    Optimal DNA + gut health testing

    From £709 £460.85

    + Free MS-01 4-week supply