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Stride Health Group

Stride Health Group Ltd
Company No 05158025
Lamas Road
Badersfield
Norwich
England
NR10 5FB
UK

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DNA Methylation & Genetic Health Testing

Find out why your energy, mood and recovery aren't where they should be.

Clear, actionable genetic insight - backed by a UK-accredited lab and delivered in 10 days.

Explore DNA Methylation Tests

Stride offers clinically grounded DNA methylation testing, designed to provide clear, actionable insight without hype or exaggeration.

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The Science

What is DNA methylation?

DNA methylation is a core biological process that helps regulate how your body processes key nutrients linked to energy, mood, and detoxification.


Your methylation capacity is largely genetic. Most notably, methylation is influenced by the MTHFR gene and reflects inherited biochemical function, not epigenetic ageing. This test is not diagnostic and does not predict disease; it’s an educational tool to support informed nutrition and lifestyle choices.

Why people test
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Nutrient processing and utilisation

Find out how efficiently your body converts and uses key nutrients like folate, B12, B6 and choline. Stride’s methylation test reveals where nutrient bottlenecks may be limiting energy, detoxification and brain function.

Provide your DNA sample

Cellular maintenance

Your methylation cycles help drive DNA repair, antioxidant production and everyday cellular maintenance. DNA testing shows where these pathways could be under extra strain, before sub-optimal functioning shows up as fatigue or poor recovery.

In-house lab testing

Stress response

Methylation pathways are central to neurotransmitter balance, adrenaline clearance and nitric oxide production. This test helps explain why stress hits you harder, and how to support calmer, more resilient stress biochemistry.

Get your personalised report

Long-term health optimisation

Efficient methylation underpins detoxification, inflammation control and healthy ageing. By understanding your methylation cycles, you can proactively support long-term health rather than reacting once problems appear.

DNA Methylation

What the test analyses
Saliva-based DNA test

This test uses a simple saliva sample collected at home and returned by post. Your DNA is stable over time, so you only need to test once to understand your inherited methylation capacity.

Analyses genes in methylation

The analysis examines key genetic control points within the methylation system, including the MTHFR gene. These variations can influence how effectively your body handles folate, B vitamins, and other methyl-dependent nutrients.

Structured, readable interpretation

Results are presented in a clear, structured format designed to be easy to understand. The report translates complex genetic data into practical, educational insights without medical diagnosis or disease prediction.

What the test analyses

Our Tests

Choose your DNA methylation test

Stride offers three DNA methylation testing options, depending on the level of genetic insight required. All tests use the same sample and interpretation standards.

Save Core DNA Methylation Test

Health Tests

Core DNA Methylation Test

5 reports: Methylation profile reports

From $229  $160

Buy Now Learn More
Save Advanced DNA & Methylation Test

Health Tests

Advanced DNA & Methylation Test

29 reports: Methylation profile and nutrigenetic reports

From $349  $244

Buy Now Learn More
Save Optimal DNA & Methylation Test

Health Tests

Optimal DNA & Methylation Test

46 reports: Methylation profile, nutrigenetic, fitness, sleep, stress and skin reports

From $479  $335

Buy Now Learn More
What gut microbiome testing shows

Microbiome tests

What gut microbiome testing shows
What gut microbiome testing shows

Gut microbiome testing analyses the balance and diversity of bacteria in your gut, often referred to as gut health. These microbes influence digestion, nutrient absorption, inflammation, and gut–brain communication.

How it complements genetics

Genetic testing shows your inherited blueprint, while microbiome testing reflects how your gut responds to diet, lifestyle, and environment. Used together, DNA and gut microbiome testing provide a broader view of gut health and nutrient processing.

That it is optional, not a replacement

Gut microbiome testing is an optional add-on for people seeking deeper insight into gut health. It complements DNA testing but does not replace it, as each test measures different biological systems.

Bundles

For those seeking a broader view, DNA methylation testing can be combined with gut microbiome analysis.

View Bundles
Bundles

Stride

From results to action: Guidance & coaching
Deeper Analysis

Personalised nutrition guidance

Your results are translated into personalised nutrition guidance tailored to your genetics and gut microbiome. This helps you make clearer, more confident food and supplement choices.

Faster turnaround

Optional 1:1 coaching

Optional 1:1 coaching is available if you want personalised support beyond your report. Sessions focus on turning insights into practical, sustainable changes.

Expert Support

Delivered by qualified dieticians

All guidance and coaching are delivered by qualified dietitians and nutrition experts. This ensures recommendations are evidence-based, responsible, and aligned with best practice.

US VS THEM

Why smart optimisers choose Stride

Get faster results, deeper insights, and real guidance, not just data. Here’s how Stride stacks up.

Stride Core DNA Methylation Test 10x Health System Ultimate Human
Genes analysed 19 5 13
Results time 10 days 4 weeks 5 weeks
1:1 Expert consultation Yes No No
Personalised plan Yes No No
Money-back guarantee Yes No No
Price $160 $599 $679

As featured in

Financial Times Forbes The Telegraph Fitt Insider Sheerluxe The Standard Red Country & Town House Luxurious Magazine InTouch Rugby

Ambassadors

Trusted by the leading minds in health and performance

From clinical pioneers to Olympic champions, Stride is the preventative health system backed by those who know best.

Dr William Li

“What excites me about Stride is how we can show people what’s happening inside their bodies and then use diet and lifestyle change to transform their future towards optimal health. It’s a platform that turns science into daily practice.”

Dr William Li

Physician, Scientist & BESTSELLING AUTHOR

Dr Rupy Aujla

“Stride is the service that finally connects the dots between testing, lifestyle and real-world behaviour change. Most services give you data; Stride gives you direction. This is the kind of preventative, personalised approach we need more of.”

Dr Rupy Aujla

NHS GP & Founder of The Doctor’s Kitchen

Greg Rutherford

“As Olympic champion, I learned that the smallest details can be the difference between good and great. Now that I’m at a different stage of my life, what I love about Stride is that it brings that same performance mindset to everyday health.”

Greg Rutherford, MBE

Olympic Gold Medallist & Broadcaster

For the curious.

What is a genetic methylation test?

A genetic methylation test analyses key genes involved in the body’s methylation pathways, which support detoxification, neurotransmitter balance, hormone regulation, and energy production.

The Stride Core Methylation Test is an at-home genetic test that examines DNA variants affecting five core methylation cycles, providing clear, actionable insights rather than raw genetic data.

Why is methylation important for health, and how do genetic variants affect it?

Methylation is a core biochemical process that supports gene expression, detoxification, energy production, immune function, neurotransmitter balance, and lipid metabolism.

Genetic variants in methylation-related genes (e.g., MTHFR, MTR, MTRR, COMT, BHMT, CBS) can influence how efficiently your body converts and uses nutrients such as folate and B12, which may affect energy, mood, cardiovascular and neurological health.

Understanding your variants helps tailor nutrition and supplementation (e.g., folate form and dose, B-vitamin support), alongside lifestyle changes to optimise methylation.

What's included with the Core Methylation Test?

Your kit includes:

  • Easy-to-use at-home DNA test kit
  • Free return mailer to our UK laboratory
  • 5 Methylation Reports: Folate Cycle, Methionine Cycle, Transsulphuration Pathway, BH4 Cycle, Urea Cycle
  • 1:1 Health Expert Support (including dietician)
  • Access to the Stride digital health platform

What methylation pathways does it analyse?

The Core Methylation Test covers the Folate Cycle, Methionine Cycle, Transsulphuration Pathway, BH4 Cycle, and Urea Cycle to help you understand where methylation efficiency may be supported.

What genes are analysed in a genetic methylation test?

This genetic methylation test analyses over 9,000 genetic locations, focusing on variants with strong scientific evidence that influence methylation efficiency.

Key genes include MTHFR, COMT, MTR, MTRR, CBS, and others involved in folate metabolism, neurotransmitter balance, and detoxification pathways.

Why is the AHCY gene not included in Stride's Methylation Report?

We include genes with strong human evidence and clear, modifiable actions.

AHCY SNPs rs41301825 and rs13043752 are regarded as benign and rare; rs121918608 is a very rare pathogenic mutation. Including benign or ultra-rare variants would not add meaningful, actionable insight for most users.

How does the Core Methylation Test differ from other DNA tests?

Stride analyses more genetic locations than most methylation-only tests and delivers results via an interactive platform with expert support, helping you translate data into practical nutrition and supplement strategies.

How can this test benefit my health?

It identifies potential inefficiencies in methylation that can affect energy, detoxification, immune function, neurotransmitters, and nutrient conversion (e.g., folate), guiding targeted diet and supplement choices.

What kind of support do I receive with my StrideDNA Test?

Every Stride test includes 1:1 consultations with qualified dieticians and health practitioners. Our experts interpret your results and help you build a personalised plan.

How long does it take to receive my results?

Your results are typically available within 10 business days after your sample arrives at our UK laboratory.

Where can I get a genetic methylation test?

You can order this genetic methylation test online for at-home use. Stride ships test kits from its UK-based laboratory and accepts samples returned by post.

The test is available across the UK and internationally, with all samples analysed in Stride’s accredited in-house laboratory.

Can I take this test if I’m under 18?

StrideDNA tests are designed for adults (18+).

If you are under 18, testing should only be arranged by a parent or legal guardian, and ideally interpreted with a qualified healthcare professional. Regulatory rules and availability for minors can vary by country.

If you’re unsure, email hey@getstride.com and we’ll advise before you order.