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of adults have genetic variations disrupting methylation, the process that controls mood, detox, and hormone balance.
Methylation Explained
Have you ever wondered why two people can follow the same diet or supplement routine — yet see completely different results? The answer may lie in how your genes regulate methylation and other nutrient-processing pathways that influence energy, detoxification, and resilience.
Beyond methylation alone, your advanced DNA profile explores how your body metabolises key vitamins, amino acids, and fats — helping you understand where inefficiencies might be holding you back.
By analysing genes such as MTHFR, COMT, and MTR, Stride highlights how your body converts nutrients into active forms, maintains neurotransmitter balance, and clears toxins. Armed with this insight, you can choose precisely the right nutrition and supplement strategies to unlock your full potential.
Reports
Your results live in MyStride, a fast, clear portal with expert guidance. No PDFs. Actionable next steps.
Real reviews from Stride users.
US VS THEM
Get faster results, deeper insights, and real guidance, not just data. Here’s how Stride stacks up.
| Stride Advanced DNA & Methylation | Ultimate Human | 10x Health System | |
|---|---|---|---|
| Genes analysed | 59 | 13 | 5 |
| Results time | 10 days | 5 weeks | 4 weeks |
| 1:1 Expert consultation | |||
| Personalised plan | |||
| Money-back guarantee | |||
| Price | USD 261.75 | £499 | $599 |
Stride is a holistic personalised health ecosystem. By joining us with a StrideDNA test you’ll unlock access to everything Stride offers, from further diagnostic testing to cutting-edge supplementation.
Choose your report insight level and order your Advanced DNA & Methylation test kit.
🧬 StrideDNA At-Home Test
We’ll ship you our easy-to-use home DNA testing kit, for a world of insights with just a simple cheek swab.
Return your StrideDNA kit using our prepaid return mailer and we’ll analyse your sample at our advanced in-house laboratory.
💉 Precision laboratory analysis
We’ll extract your DNA and analyse your sample for over 9000 genetic locations, all within ten working days
📊 Genetic reports
You'll get over 50 detailed genetic reports including methylation profile.
Once you’ve got your StrideDNA results, you’ll unlock a world of personalised health insights with clear support for next steps.
💧 Supplements
With your results, you’ll unlock eligibility for one of our tailored supplements, either StrideDaily or MS-01.
🩺 1:1 Expert Consultation
Our team of holistic functional health practitioners are available for free consultations to help reach your goals.
Health Tests
Advanced Gut Health
At-home gut health test revealing microbiome diversity, gut-brain connection, and digestion insights.
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Health Tests
Advanced Blood Biomarkers
Comprehensive analysis of 70+ biomarkers for heart, hormonal, nutrients, and longevity insights. Professional, at-home blood draw.
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Supplements
Subscribe & Save
Daily support stack with active-form vitamin B6, B9 & B12 to support methylation.
Learn MoreWhat is the Advanced DNA & Methylation Test?
The Advanced DNA & Methylation Test combines deep methylation analysis with nutrigenetic insights to show how your genes influence nutrient needs, sensitivities, metabolism, and detoxification.
Why is methylation important for health, and how do genetic variants affect it?
Methylation is a core biochemical process that supports gene expression, detoxification, energy production, immune function, neurotransmitter balance, and lipid metabolism.
Genetic variants in methylation-related genes (e.g., MTHFR, MTR, MTRR, COMT, BHMT, CBS) can influence how efficiently your body converts and uses nutrients such as folate and B12, which may affect energy, mood, cardiovascular and neurological health.
Understanding your variants helps tailor nutrition and supplementation (e.g., folate form and dose, B-vitamin support), alongside lifestyle changes to optimise methylation.
What's included with the Advanced DNA & Methylation Test?
You'll receive:
What methylation pathways does it analyse?
It covers the Folate Cycle, Methionine Cycle, Transsulphuration Pathway, BH4 Cycle, and Urea Cycle as the foundation for methylation-related insights.
What methylation genes are included?
The Advanced test includes the same core methylation gene panel as the Core test (e.g., MTHFR C677T/A1298C, MTR, MTRR, COMT, BHMT, CBS, MAOA, MAOB, DHFR, FUT2, NOS3, PEMT, SOD2, TCN2, VDR) within an analysis of 9,000+ loci.
Why is the AHCY gene not included in Stride's Methylation Report?
Our inclusion criteria require strong, actionable human evidence.
AHCY SNPs rs41301825 and rs13043752 are considered benign and rare; rs121918608 is a very rare pathogenic mutation. They do not provide broadly applicable, modifiable insights for most users.
How does the Advanced test differ from the Core test?
Advanced includes everything in Core plus 24 nutrigenetic reports to guide diet, sensitivities, detox capacity, and supplement planning for a wider, more practical action plan.
How can this test benefit my health?
It helps you personalise nutrition (e.g., folate and B-vitamins), manage food and stimulant sensitivities, and support detoxification pathways—informing targeted diet and supplement strategies.
What kind of support do I receive with my StrideDNA Test?
All Stride tests include 1:1 consultations with qualified dieticians and health practitioners to translate your results into a tailored plan.
How long does it take to receive my results?
Expect your personalised reports within 10 business days of sample receipt at our UK laboratory.
Where is the methylation test available?
We ship worldwide from the UK. Availability spans the UK, Europe, North America, Asia-Pacific, Oceania, South America, and Africa. Delivery times and customs fees vary. If your country is missing, email hey@getstride.com.
Can I take this test if I’m under 18?
StrideDNA tests are designed for adults (18+).
If you are under 18, testing should only be arranged by a parent or legal guardian, and ideally interpreted with a qualified healthcare professional. Regulatory rules and availability for minors can vary by country.
If you’re unsure, email hey@getstride.com and we’ll advise before you order.