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Stride Health Group

Stride Health Group Ltd
Company No 05158025
Lamas Road
Badersfield
Norwich
England
NR10 5FB
UK

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Advanced DNA & Methylation Test

Unlock deeper energy, focus, and resilience

See how your DNA drives methylation and nutrient metabolism

  • Analyse the five key methylation cycles PLUS more than 20 nutrigenetic reports
  • Understand how variants across 50+ genes including MTHFR and COMT affect your health and lifestyle
  • Learn how to fine-tune your nutrition and supplement choices to support optimal methylation & wellness

Save 25%

Advanced DNA & Methylation

29 reports: Methylation profile and nutrigenetic reports

USD 349 USD 261.75

Save 30%

Optimal DNA & Methylation

46 reports: Methylation profile, nutrigenetic, fitness, sleep, stress and skin reports

USD 479 USD 335.30

Or, bundle with Optimal Biome microbiome test

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30-day money-back guarantee

As featured in

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50%+

of adults have genetic variations disrupting methylation, the process that controls mood, detox, and hormone balance.

  • Constant fatigue
  • Low mood / stress
  • Hormonal imbalance
  • Slow recovery
Order My Kit

Methylation Explained

Go deeper into your DNA to enhance methylation and energy balance

Have you ever wondered why two people can follow the same diet or supplement routine — yet see completely different results? The answer may lie in how your genes regulate methylation and other nutrient-processing pathways that influence energy, detoxification, and resilience.

Beyond methylation alone, your advanced DNA profile explores how your body metabolises key vitamins, amino acids, and fats — helping you understand where inefficiencies might be holding you back.

By analysing genes such as MTHFR, COMT, and MTR, Stride highlights how your body converts nutrients into active forms, maintains neurotransmitter balance, and clears toxins. Armed with this insight, you can choose precisely the right nutrition and supplement strategies to unlock your full potential.

Reports

There’s more to methylation testing with Stride

Your results live in MyStride, a fast, clear portal with expert guidance. No PDFs. Actionable next steps.

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Methylation Profile Reports

Understand how your folate, methionine, BH4, and transsulphuration cycles are wired.


Helps with: DNA repair, detox, neurotransmitters, energy.

Includes: 5 reports

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Nutrition Reports

See how your genes shape vitamin/mineral needs and carb/fat handling.


Helps with: intake, intolerances, better absorption.

Includes: 24 reports

Available with Advanced/Optimal

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Fitness Reports

Train the way your body responds best. Avoid wasted effort and plateaus.


Helps with: intensity, recovery, injury risk, programming.

Includes: 4 reports

Available with Optimal

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Sleep & Stress Reports

Work with your natural rhythm and resilience. Wake restored; stay calm daily.


Helps with: chronotype, sleep quality, coping under stress.

Includes: 5 reports

Available with Optimal

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Skin Reports

Target what your skin actually needs. Personalised care for visible results.


Helps with: DNA repair, detox, neurotransmitters, energy.

Includes: 5 reports

Available with Optimal

Join tens of thousands already taking control of their health.

Real reviews from Stride users.

US VS THEM

Why smart optimisers choose Stride

Get faster results, deeper insights, and real guidance, not just data. Here’s how Stride stacks up.

Stride Advanced DNA & Methylation Ultimate Human 10x Health System
Genes analysed 59 13 5
Results time 10 days 5 weeks 4 weeks
1:1 Expert consultation Yes No No
Personalised plan Yes No No
Money-back guarantee Yes No No
Price USD 261.75 £499 $599
Order My Kit

Full stack precision health

Stride is a holistic personalised health ecosystem. By joining us with a StrideDNA test you’ll unlock access to everything Stride offers, from further diagnostic testing to cutting-edge supplementation.

Phase 1: Assessment

Choose your report insight level and order your Advanced DNA & Methylation test kit.

  • 🧬 StrideDNA At-Home Test

    We’ll ship you our easy-to-use home DNA testing kit, for a world of insights with just a simple cheek swab.

Phase 2: Discovery

Return your StrideDNA kit using our prepaid return mailer and we’ll analyse your sample at our advanced in-house laboratory.

  • 💉 Precision laboratory analysis

    We’ll extract your DNA and analyse your sample for over 9000 genetic locations, all within ten working days

  • 📊 Genetic reports

    You'll get over 50 detailed genetic reports including methylation profile.

Phase 3: Action 

Once you’ve got your StrideDNA results, you’ll unlock a world of personalised health insights with clear support for next steps.

  • 💧 Supplements

    With your results, you’ll unlock eligibility for one of our tailored supplements, either StrideDaily or MS-01.

  • 🩺 1:1 Expert Consultation

    Our team of holistic functional health practitioners are available for free consultations to help reach your goals.

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Comprehensive analysis of 70+ biomarkers for heart, hormonal, nutrients, and longevity insights. Professional, at-home blood draw.

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Supplements

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MS-01

Daily support stack with active-form vitamin B6, B9 & B12 to support methylation.

Learn More

For the curious.

What is the Advanced DNA & Methylation Test?

The Advanced DNA & Methylation Test combines deep methylation analysis with nutrigenetic insights to show how your genes influence nutrient needs, sensitivities, metabolism, and detoxification.

Why is methylation important for health, and how do genetic variants affect it?

Methylation is a core biochemical process that supports gene expression, detoxification, energy production, immune function, neurotransmitter balance, and lipid metabolism.

Genetic variants in methylation-related genes (e.g., MTHFR, MTR, MTRR, COMT, BHMT, CBS) can influence how efficiently your body converts and uses nutrients such as folate and B12, which may affect energy, mood, cardiovascular and neurological health.

Understanding your variants helps tailor nutrition and supplementation (e.g., folate form and dose, B-vitamin support), alongside lifestyle changes to optimise methylation.

What's included with the Advanced DNA & Methylation Test?

You'll receive:

  • At-home DNA test kit + free UK lab return
  • 5 Methylation Reports: Folate, Methionine, Transsulphuration, BH4, Urea
  • 24 Nutrigenetic Reports covering: vitamin/mineral needs (A, B2, B6, B9, B12, C, D, E, iron, omega 3), sensitivities (lactose, coeliac predisposition, fructose, caffeine, alcohol, salt, sugar), and detoxification phases I & II
  • 1:1 Health Expert Support (including dietician)
  • Stride digital health platform

What methylation pathways does it analyse?

It covers the Folate Cycle, Methionine Cycle, Transsulphuration Pathway, BH4 Cycle, and Urea Cycle as the foundation for methylation-related insights.

What methylation genes are included?

The Advanced test includes the same core methylation gene panel as the Core test (e.g., MTHFR C677T/A1298C, MTR, MTRR, COMT, BHMT, CBS, MAOA, MAOB, DHFR, FUT2, NOS3, PEMT, SOD2, TCN2, VDR) within an analysis of 9,000+ loci.

Why is the AHCY gene not included in Stride's Methylation Report?

Our inclusion criteria require strong, actionable human evidence.

AHCY SNPs rs41301825 and rs13043752 are considered benign and rare; rs121918608 is a very rare pathogenic mutation. They do not provide broadly applicable, modifiable insights for most users.

How does the Advanced test differ from the Core test?

Advanced includes everything in Core plus 24 nutrigenetic reports to guide diet, sensitivities, detox capacity, and supplement planning for a wider, more practical action plan.

How can this test benefit my health?

It helps you personalise nutrition (e.g., folate and B-vitamins), manage food and stimulant sensitivities, and support detoxification pathways—informing targeted diet and supplement strategies.

What kind of support do I receive with my StrideDNA Test?

All Stride tests include 1:1 consultations with qualified dieticians and health practitioners to translate your results into a tailored plan.

How long does it take to receive my results?

Expect your personalised reports within 10 business days of sample receipt at our UK laboratory.

Where is the methylation test available?

We ship worldwide from the UK. Availability spans the UK, Europe, North America, Asia-Pacific, Oceania, South America, and Africa. Delivery times and customs fees vary. If your country is missing, email hey@getstride.com.

Can I take this test if I’m under 18?

StrideDNA tests are designed for adults (18+).

If you are under 18, testing should only be arranged by a parent or legal guardian, and ideally interpreted with a qualified healthcare professional. Regulatory rules and availability for minors can vary by country.

If you’re unsure, email hey@getstride.com and we’ll advise before you order.