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Stride Health Group

Stride Health Group Ltd
Company No 05158025
Lamas Road
Badersfield
Norwich
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NR10 5FB
UK

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Why choose this bundle

Methylation is a foundational biochemical process, driving detoxification, neurotransmitter production, nutrient conversion, energy metabolism and more. Our Core Methylation DNA test maps your genetic profile across 5 key methylation pathways: Folate Cycle, Methionine Cycle, Transsulphuration, BH4 and Urea.

MS-01 supports these cycles with a specially formulated daily supplement with bio-available forms of Vitamins B6, B9 (methylfolate), B12 (methylcobalamin), plus Trimethylglycine (TMG) and Vitamin C, crafted to support your methylation capacity.

Insight + Action = Real health optimisation.

Key benefits

Understand your unique methylation profile and genetic predispositions.

Support your methylation daily with premium nutrients in the most bioavailable active form.

Optimise energy, detox, improve mood & cellular function.

Save money by bundling the test + supplement.

Peace of mind: results from an in-house UK lab, plus easy-to-use at-home test kits.

Methylation Stack

Unlock your methylation blueprint + daily support

Discover how your genes influence methylation, then support them every day with our advanced methylated B-complex

Excellent  Score 4.8 out of 5

Okendo
Trustpilot
  • Complete methylation solution: our most comprehensive DNA test plus 3 months’ supply of our methylated supplement MS-01
  • At-home DNA test kit + MS-01 delivered directly to your door

Save 30%

Methylation Stack

Optimal DNA & methylation test including 46 reports, plus 3 months’ supply of MS-01, our methylated B vitamin complex

USD 569 USD 398.30

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30-day money-back guarantee

Why choose this bundle

Methylation is a foundational biochemical process, driving detoxification, neurotransmitter production, nutrient conversion, energy metabolism and more. Our Core Methylation DNA test maps your genetic profile across 5 key methylation pathways: Folate Cycle, Methionine Cycle, Transsulphuration, BH4 and Urea.

MS-01 supports these cycles with a specially formulated daily supplement with bio-available forms of Vitamins B6, B9 (methylfolate), B12 (methylcobalamin), plus Trimethylglycine (TMG) and Vitamin C, crafted to support your methylation capacity.

Insight + Action = Real health optimisation.

Key benefits

Understand your unique methylation profile and genetic predispositions.

Support your methylation daily with premium nutrients in the most bioavailable active form.

Optimise energy, detox, improve mood & cellular function.

Save money by bundling the test + supplement.

Peace of mind: results from an in-house UK lab, plus easy-to-use at-home test kits.

As featured in

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Methylation Stack

What’s included in the Methylation Stack

Optimal DNA & Methylation

Health Tests

Optimal DNA & Methylation
  • At-home cheek swab
  • UK accredited lab
  • 5 methylation pathway reports
MS-01

Supplements

MS-01 Daily Support
  • Daily capsule with methylated B vitamins & vitamin C
  • Bio-active B6, methylfolate, B12, TMG, Vitamin C.
  • Take one capsule daily with or without food.
Buy Methylation Stack Now

Optimised health. It’s yours to take.

Take your health to the next level, with our advanced DNA screening test

Your DNA holds the blueprint of how your body truly works. Stride's Optimal DNA & Methylation reveals that blueprint in remarkable detail - combining advanced methylation analysis with extended genetic insights into nutrition, sleep, stress, fitness, and skin health. It’s the most complete at-home methylation test available, designed to help you understand, optimise, and master your biology.

Methylation is one of the body’s most important regulatory systems - controlling gene expression, detoxification, energy production, and cellular repair. When methylation is efficient, your body performs at its best. When it isn’t, fatigue, inflammation, and poor recovery can take hold. Your Optimal DNA & Methylation results show exactly how well these cycles are working, highlighting key pathways such as the Folate, Methionine, BH4, and Transsulphuration cycles, plus how your genes interact across more than 9,000 genetic markers.

But this test doesn’t stop at methylation. With over 45 individual DNA reports, you’ll also uncover how your genetics influence metabolism, nutrient needs, collagen formation, recovery efficiency, sleep rhythm, and resilience to stress - the core systems that determine your energy, longevity, and daily performance.

Stride goes far beyond standard DNA kits. We operate our own UK-based laboratory for faster turnaround (typically within ten business days) and deliver your results through an interactive digital health platform - not a static PDF. Each test includes 1:1 expert support from our dieticians and human-health practitioners, helping you turn genetic data into clear, actionable steps. It’s precision health, made personal - the smarter way to optimise your methylation and perform at your genetic best.

Reports

There’s more to methylation testing with Stride

Your results live in MyStride, a fast, clear portal with expert guidance. No PDFs. Actionable next steps.

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Methylation Profile Reports

Understand how your folate, methionine, BH4, and transsulphuration cycles are wired.

Helps with: DNA repair, detox, neurotransmitters, energy.

Includes: 5 reports

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Nutrition Reports

See how your genes shape vitamin/mineral needs and carb/fat handling.

Helps with: intake, intolerances, better absorption.

Includes: 24 reports

Available with Advanced/Optimal

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Fitness Reports

Train the way your body responds best. Avoid wasted effort and plateaus.

Helps with: intensity, recovery, injury risk, programming.

Includes: 4 reports

Available with Optimal

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Sleep & Stress Reports

Work with your natural rhythm and resilience. Wake restored; stay calm daily.

Helps with: chronotype, sleep quality, coping under stress.

Includes: 5 reports

Available with Optimal

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Skin Reports

Target what your skin actually needs. Personalised care for visible results.

Helps with: DNA repair, detox, neurotransmitters, energy.

Includes: 5 reports

Available with Optimal

Why Stride?

Deeper Analysis

Deeper Analysis

Most methylation tests on the market look at only a handful of genetic variants. StrideDNA analyse more than 9,000 genetic locations with every sample for the most precision picture of your health.

Data Security

Data Security

We use strong technical and organisational measures to keep your data safe. It is stored securely and encrypted, and only accessible by the minimum necessary members of our team.

Expert Support

Expert Support

Forget hard to understand lab reports on a static PDF, with no support. StrideDNA results are delivered in your own interactive, world-class portal and every test includes 1:1 support from our expert team of human health practitioners.

Faster turnaround

Faster turnaround

Unlike almost every other test provider, we own and operate our own in-house laboratory here in the UK. This means we can be higher quality, lower cost and deliver results faster than anyone else.

Join tens of thousands already taking control of their health.

Real reviews from Stride users.

Trustpilot

US VS THEM

Why smart optimisers choose Stride

Get faster results, deeper insights, and real guidance, not just data. Here’s how Stride stacks up.

Stride Methylation Stack Ultimate Human 10x Health System
Genes analysed 13 5
Results time 10 days 5 weeks 4 weeks
1:1 Expert consultation Yes No No
Personalised plan Yes No No
Money-back guarantee Yes No No
Price USD 398.30 £499 $599
Order My Kit

Full stack precision health

Stride is a holistic personalised health ecosystem. By joining us with a StrideDNA test you’ll unlock access to everything Stride offers, from further diagnostic testing to cutting-edge supplementation.

Phase 1: Assessment

Choose your report insight level and order your Optimal DNA & Methylation test kit.

  • 🧬 StrideDNA At-Home Test

    We’ll ship you our easy-to-use home DNA testing kit, for a world of insights with just a simple cheek swab.

Phase 2: Discovery

Return your StrideDNA kit using our prepaid return mailer and we’ll analyse your sample at our advanced in-house laboratory.

  • 💉 Precision laboratory analysis

    We’ll extract your DNA and analyse your sample for over 9000 genetic locations, all within ten working days

  • 📊 Genetic reports

    You'll get over 50 detailed genetic reports including methylation profile.

Phase 3: Action 

Once you’ve got your StrideDNA results, you’ll unlock a world of personalised health insights with clear support for next steps.

  • 💧 Supplements

    With your results, you’ll unlock eligibility for one of our tailored supplements, either StrideDaily or MS-01.

  • 🩺 1:1 Expert Consultation

    Our team of holistic functional health practitioners are available for free consultations to help reach your goals.

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Comprehensive analysis of 70+ biomarkers for heart, hormonal, nutrients, and longevity insights. Professional, at-home blood draw.

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Supplements

Subscribe & Save

MS-01

Daily support stack with active-form vitamin B6, B9 & B12 to support methylation.

Learn More

For the curious.

What is the Optimal DNA & Methylation Test?

Our most comprehensive option combining methylation, nutrigenetics, fitness, sleep & stress, and skin genetics to give a complete view of your health blueprint.

Why is methylation important for health, and how do genetic variants affect it?

Methylation is a core biochemical process that supports gene expression, detoxification, energy production, immune function, neurotransmitter balance, and lipid metabolism.

Genetic variants in methylation-related genes (e.g., MTHFR, MTR, MTRR, COMT, BHMT, CBS) can influence how efficiently your body converts and uses nutrients such as folate and B12, which may affect energy, mood, cardiovascular and neurological health.

Understanding your variants helps tailor nutrition and supplementation (e.g., folate form and dose, B-vitamin support), alongside lifestyle changes to optimise methylation.

What's included with the Optimal DNA & Methylation Test?

Your package includes:

  • At-home DNA test kit + prepaid UK lab return
  • 5 Methylation Reports
  • 24 Nutrigenetic Reports
  • 4 Genetic Fitness Reports: Power/Endurance, Aerobic Training Response, Recovery Efficiency, Injury Predisposition
  • 5 Genetic Mental Cognition (Sleep + Stress) Reports: Chronotype, Sleep Quality, Caffeine & Sleep Response, Stress Tolerance, Warrior/Strategist
  • 7 Genetic Skin Reports: Skin Ageing, Oxidative Stress Impact, Carb/Glycation Sensitivity, Pigmentation, Nickel Sensitivity, Detoxification, Inflammation
  • 1:1 Health Expert Support (including dietician)
  • Stride digital health platform

What methylation pathways does it analyse?

The Optimal test includes the full methylation foundation: Folate Cycle, Methionine Cycle, Transsulphuration Pathway, BH4 Cycle, and Urea Cycle.

What methylation genes are included?

It includes the same core methylation gene panel used in Core/Advanced—e.g., MTHFR (C677T, A1298C), MTR, MTRR, COMT, BHMT, CBS, MAOA, MAOB, DHFR, FUT2, NOS3, PEMT, SOD2, TCN2, and VDR—within a 9,000+ locus analysis.

Why is the AHCY gene not included in Stride's Methylation Report?

To maximise relevance and actionability, we exclude variants deemed benign or extremely rare with serious pathology.

AHCY SNPs rs41301825 and rs13043752 are benign and uncommon; rs121918608 is a rare pathogenic mutation, so it isn't appropriate for routine reporting.

How does the Optimal test differ from the Advanced test?

Optimal includes everything in Advanced and adds fitness performance/recovery, sleep & stress traits, and skin ageing/inflammation insights for a complete, longevity-focused view.

How can this test benefit my health?

You'll get precise guidance for nutrition and supplements plus insights to optimise training, recovery, sleep quality, stress resilience, and skin health.

What kind of support do I receive with my StrideDNA Test?

All plans include 1:1 consultations with qualified dieticians and health practitioners who help interpret your reports and turn them into an actionable plan.

How long does it take to receive my results?

Results are typically delivered within 10 business days after your sample reaches our UK laboratory.

Where is the methylation test available?

Global shipping from the UK across the UK, Europe, North America, Asia-Pacific, Oceania, South America, and Africa. Delivery times and customs charges vary. For unlisted countries, contact hey@getstride.com.

Can I take this test if I’m under 18?

StrideDNA tests are designed for adults (18+).

If you are under 18, testing should only be arranged by a parent or legal guardian, and ideally interpreted with a qualified healthcare professional. Regulatory rules and availability for minors can vary by country.

If you’re unsure, email hey@getstride.com and we’ll advise before you order.